Polysulfated glycosaminoglycan/PSGAG (brand names: Adequan®, Chondroprotec®) is an arthritis medication used to prevent joint degeneration and protect articular cartilage.
Together with weight management, physical therapy, and medications to treat pain and inflammation, Adequan can be a valuable addition to available therapies for dogs with osteoarthritis.
While the specific mechanism of action of Adequan® in canine joints is unknown, clinical data shows that Adequan® reaches all canine synovial joints within 2 hours. b> to help repair damaged or inflamed joint tissue – and lasts approximately 3 days.
Adequan for dogs is an injectable medication that may help slow the progression of osteoarthritis. It also helps reduce joint pain and other arthritis symptoms. The integrative vet Dr. Julie Buzby breaks it all down so you’ll be well-informed when your vet prescribes Adequan for your dog.
Polysulfated glycosaminoglycan/PSGAG (brand names: Adequan®, Chondroprotec®) is an anti-arthritis medication used to prevent joint degeneration and protect articular cartilage.
We recommend Pentosan as a main treatment for arthritis in dogs and cats. It will improve the joints of all affected pets, but some show more significant pain relief depending on the severity of the arthritis. A series of 4 injections once a week is required to initiate the “cure”.
In post-marketing experience, fatalities have been reported in some cases; Vomiting, anorexia, depression/lethargy and diarrhea have also been reported.
Physical therapy and appropriate forms of regular exercise, as mentioned earlier, can be extremely beneficial for dogs with arthritis. Many owners also find hydrotherapy or water therapy helpful. Holistic therapies such as acupuncture can also be helpful.
Adequan and Pentosan are actually more effective than oral glucosamine supplements. PSGAGs are the final molecules to reach the joint and reduce inflammation. Glucosamine is the precursor to PSGAGs and therefore has to go through many metabolic steps to reach the final, active product in the joint.
How much does it cost? A 5ml bottle of Adequan costs $70.00 and contains five doses for Haley’s weight of 50 pounds. So each monthly dose costs about $14.00 after the initial batch of shots is completed.
Hello, yes, you can start using Adequan for Stella’s Arthritis very safely. I would much prefer that you speak to Stella’s vet before using Prexicox. If you were my client I would recommend either increasing gabapentin (if applicable) or using the latest NSAID called Galliprant.
How is Adequan® Canine different from a nonsteroidal anti-inflammatory drug (NSAID)? Adequan® Canine is a PSGAG prescription formulation. It is a disease-modifying osteoarthritis drug (DMOAD) that inhibits the loss of cartilage in a dog’s joints. The specific mechanism of action of Adequan® in canine joints is unknown.
There are conflicting clinical reports on its effectiveness when used for this purpose, although some studies report an improvement in up to 50% of dogs studied. In dogs, orally administered gabapentin is well absorbed from the duodenum, with peak levels occurring approximately one to two hours after administration.
Precautions. Do not mix this drug with other drugs or chemicals. Do not use in animals hypersensitive to this drug or suspected of having a bleeding disorder.
Corticosteroids can be life-saving medications and improve the quality of life for many dogs. By working closely with your veterinarian, you can safely administer these medications and provide your dog with the quality care they need and deserve.
With the exception of the dosing regimen there are no significant differences between Adequan for horses and dogs, says Dr. Gary Kaufman, a veterinarian in Scottsdale, Arizona. Injections of Adequan etc. go directly into the joint, while Adequan i.m. and Adequan Canine are injected into the muscle.
Quickly reaches your horse’s joints for relief
After intramuscular administration, Adequan® is administered i.m. It is absorbed well, works quickly and lasts up to 96 hours. Hyaluronic acid (HA) levels almost doubled after 48 hours, with a significant increase between 24 and 96 hours.
An arthritic dog may have trouble climbing stairs and jumping on furniture. As the arthritis progresses, your dog may be very stiff throughout the day, take short, choppy strides, and have trouble pacing. Stairs can be difficult to impossible. End-stage arthritis can leave you unable to stand at all.