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in which the acetylsalicylic acid reacts with the base sodium hydr oxide to make the salt sodium acetylsalicylate and water (acid + base → salt + water).
In the back titration of aspirin, a known excess of NaOH is added to the sample solution to ensure that both reactions have gone to completion.
Sodium hydroxide reacts with strong acids (hydrochloric, sulfuric or nitric acid), water and moisture to rapidly release heat. Sodium hydroxide reacts with metals (aluminium, lead, tin or zinc) to form flammable and explosive hydrogen gas.
(A) Aspirin can easily enter cells and react with many different cellular chemicals. For example, aspirin can react with water to form the hydrolysis by-product salicylic acid. Aspirin can also react with nucleophilic metabolites (e.g. glutathione) or proteins to produce acetylated products.
Closed 4 years ago. The chemistry lab note states that: 1) Aromatic acids such as benzoic acid and salicylic acid are NOT soluble in water. But they are soluble in 5% NaOH and 5% NaHCO3.
Aspirin would be easily soluble in NaOH as the carboxylic acid group would be deprotonated and thus negatively charged.
Aspirin itself is an acid drug and causes gastric irritation and belching, which can lead to low oral pH .
Solution: `C_(2)H_(5)OH` (Ethanol) is a very weak acid, so it does not react with NaOH.
Aluminum does not react with sodium hydroxide.
Only the metals whose oxides/hydroxides are amphoteric will react with strong water-soluble bases (alkalis) to liberate hydrogen gas.
Aspirin is soluble in organic solvents such as ethanol, DMSO and dimethylformamide which should be purged with an inert gas. The solubility of aspirin in these solvents is approximately 80, 41, and 30 mg/mL, respectively.
Aspirin (acetylsalicylic acid) reacts with water (eg, water in body fluids) to form salicylic acid and acetic acid, as shown in Figure 5.2. 2. Figure 5.2. 2: Hydrolysis of the aspirin reaction.
There are several types of aspirin tablets including: Standard tablets that you swallow whole with water. dissolvable tablets that you dissolve in a glass of water.
Aspirin was introduced into clinical practice more than 100 years ago. This unique drug belongs to a family of compounds called salicylates, the simplest of which is salicylic acid, the main metabolite of aspirin.
Since salicylic acid is not sufficiently water soluble at room temperature to achieve the desired composition, it must be converted to salicylate. This can be done by reacting sodium bicarbonate (baking soda) with salicylic acid in water – the salicylic acid will dissolve during the reaction.
Salicylic acid is notoriously difficult to dissolve. Salicylic acid powder is best dissolved with a mixture of alcohol, water and propylene glycol. If you find it difficult to find, vegetable oil is believed to be a good substitute for propylene glycol.